GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLCA | cis | rs10935120 | 1 | rs2056603 | chr3:134312749 | ANAPC13 | chr3:134196547-134204865:- | 0.48 | 7.6 | 2.33E-13 | Height |
| BLCA | cis | rs10935120 | 1 | rs2056604 | chr3:134312648 | ANAPC13 | chr3:134196547-134204865:- | 0.48 | 7.6 | 2.33E-13 | Height |
| BLCA | cis | rs4722750 | 1 | rs2057671 | chr7:27999195 | HIBADH | chr7:27565063-27702602:- | -0.37 | -3.83 | 0.000152 | Thiazide-induced adverse metabolic effects in hypertensive patients |
| BLCA | cis | rs2058059 | 1 | rs2058059 | chr7:72311817 | TYW1B | chr7:72023729-72298813:- | -0.43 | -5.3 | 1.98E-7 | Subcutaneous adipose tissue |
| BLCA | cis | rs9783347 | 1 | rs2061164 | chr11:18329006 | GTF2H1 | chr11:18343816-18388590:+ | 0.32 | 6.11 | 2.46E-9 | Pancreatic cancer |
| BLCA | cis | rs2762051 | 1 | rs2066656 | chr13:50804716 | CAB39L | chr13:49882787-50018221:- | 0.24 | 4.59 | 5.93E-6 | Celiac disease |
| BLCA | cis | rs703842 | 1 | rs2069502 | chr12:58144665 | FAM119B | chr12:58166383-58176323:+ | -0.26 | -4.07 | 5.71E-5 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs2069502 | chr12:58144665 | TSFM | chr12:58176536-58191367:+ | 0.38 | 6.74 | 5.79E-11 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs2069502 | chr12:58144665 | XRCC6BP1 | chr12:58335445-58351051:+ | 0.23 | 3.95 | 9.32E-5 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs2072052 | chr12:58146719 | FAM119B | chr12:58166383-58176323:+ | 0.25 | 3.84 | 0.000145 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs2072052 | chr12:58146719 | TSFM | chr12:58176536-58191367:+ | -0.4 | -7.03 | 9.42E-12 | Multiple sclerosis |
| BLCA | cis | rs703842 | 1 | rs2072052 | chr12:58146719 | XRCC6BP1 | chr12:58335445-58351051:+ | -0.25 | -4.24 | 2.82E-5 | Multiple sclerosis |
| BLCA | cis | rs2239557 | 1 | rs2072293 | chr14:74537885 | LIN52 | chr14:74551656-74667117:+ | 0.34 | 7.86 | 4.03E-14 | Common traits (Other) |
| BLCA | cis | rs7789940 | 1 | rs2072435 | chr7:75959188 | UPK3B | chr7:76139745-76157197:+ | -0.3 | -6.18 | 1.67E-9 | Multiple sclerosis |
| BLCA | cis | rs7112513 | 1 | rs2075292 | chr11:116732512 | PCSK7 | chr11:117075789-117102811:- | -0.42 | -5.45 | 8.84E-8 | Protein quantitative trait loci |